Scalable Agitated Baffle Reactor

Combines the benefits of batch and flow:

Flexibility of batch. SABRe is multipurpose, and scalable. All the batch engineering and applies.

Performance of flow. SABRe heat and mass transfer is close to that of tubular and chip reactors.


Result: higher product quality, faster development, higher throughput.

Best in class performance

Proven in the liquid-liquid enzymatic esterification comparing batch, chip, and other agitated continuous reactors!

To move rapidly from laboratory, to pilot, to production scale.

  • Rapid scalability
  • Speeding-up complex and exothermic process
  • Process intensification – high throughput at low cost

SABRe: series of continuous stirred tanks (CSTRs) reimagined: simple, multi-purpose, scalable

Scheme of sabre system

Each chamber is a stirred tank

Mixing independent on flow rates

Reagents could be added or removed

That enables simple & efficient reaction cascades

Precise contol of residence time

Several temperature zones

Rapid heat transfer with standard circulators

Modular design for many applications

Designed to work as a drop in replacement for jacketed batch reactors, SABRe is compatible with major pumps, chillers, heaters and overhead stirrers. You don’t have to invest in a new suite of equipment to explore continuous manufacture.

One pressure vessel provides

  • several reactor volumes
  • various impellers
  • various inlet/outlet points
  • various number of chambers
  • different baffle geometry

… all with a removable insert

Interfacial mass transfer performance of the SABRe

Rapid scale-up of precision chemical manufacturing

SABRe provides unrivalled reaction control, even at long residence times and large scale.

Mixing independent on pumping rates enables consistent, controllable, and predictable mass transfer performance.

Several jacket options enable high heat transfer rates for handling hazardous and exothermic reactions.

The SABRe system is offered in 3 standard sizes for lab, pilot and production scale, allowing the user a clear route to scale up without sacrificing yield, purity or energy efficiency. 

Saves materials, energy and labour costs

Example process -aromatic  hydrogenation of cresol

Savings are proven independently

(similar reactor concept): Machefer, S., Falk, L., & de Panthou, F. (2013). DOI: 10.1016/j.cep.2012.06.005

Predictable performance fully characterised


Primary Wetted Material

316 Stainless or C276 Hastelloy
Glass or Quartz

Secondary Wetted MaterialPTFE / FFKM
Reactor Volume

Lab: 20 – 120 mL
Pilot: 1.5 – 10 L
Production: 15 – 100 L



Download specifications (pdf)

Specifications: size, mass, operating parameters

Lab system 100 mL

Internal volume

20 or 120 mL with various inserts


-190 to 200 C

Pressure (material dependent)

Standard: vacuum to 20 bar

Bespoke: up to 100 bar

Residence time

30 s to 5 hr in continuous

Could be use in batch-mode!

Mixing Speed

10 to 1500 RPM


Reactor & Stand         300 x 300 x 850 mm

Skid (turnkey system) 450 x 680 x 1910 mm


Reactor & Stand         15 kg

Skid                             35 kg


Swagelok 1/8” or 1/4″ in. reagent port

Swagelok 1/8” or 1/4″ in. reagent port

M16x1 or 12mm pipe for circulator


almost any overhead stirrer, such as  IKA


any liquid pumps such as HPLC or peristaltic



Pilot system: 1L

Piloting starts in 2022. There are still 2 opportunities to join the piloting programme and benefit from scalable & multipurpose continuous processing. 

Pilot system: 10L

Piloting in progress. There are still 2 opportunities to join the piloting programme and benefit from scalable & multipurpose continuous processing.